3365 Drew St

San Marco sits south of downtown Jacksonville along the St. Johns River, with leafy residential streets and a compact commercial district around San Marco Square. The riverfront setting brings humid, warm summers and mild winters. Historic buildings and the district’s distinctive bronze lion statues give the square a recognizable character, while nearby parks and river views offer room to stroll outdoors. Cafés, restaurants, boutiques and galleries cluster near the square, with additional shopping and everyday services along the surrounding corridors. The Cummer Museum of Art and Gardens is just across the river, and downtown venues are a short trip away. Residents get around by car, bus, bicycle or on foot in the central district. San Marco neighborhood listings show a median rent of $1,560 per month and a typical range of $725 to $4,900.