E Palmetto St, Florence, SC 29506

High-Visibility Commercial Parcel – E. Palmetto Street & Dunton Drive, Florence, SC This exceptional ±12.65-acre commercial parcel offers 493 feet of frontage on E. Palmetto Street and 1,063 feet on Dunton Drive, positioned just off the corner of Hwy 327 and E. Palmetto Street. Located approximately 5 miles from I-95 Exit 170 (327)—the same exit as Buc-ee’s—this site enjoys consistently high traffic volume from automobiles, commercial vehicles, and motorhomes, with seasonal increases from beach-bound travelers. Surrounded by a dynamic mix of established and emerging residential communities, including the Sandstone Community (150 homes) and Greystone Townhomes (100 units under construction), this location is ideal for high-demand commercial uses such as a grocery store, pharmacy, urgent care center, or other essential services. The property is also in close proximity to major employment and institutional anchors: AESC EV battery plant & training center, Amazon distribution facilities, Pee Dee Commerce Center East & West, Francis Marion University (FMU), McLeod Health & MUSC Health and Florence’s downtown entertainment district. With its unmatched visibility, accessibility, and surrounding growth, this parcel presents a rare opportunity for developers and investors to capitalize on Florence’s expanding commercial corridor.